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Bridget Kendall and her guests explore extreme living and what it tells us, from human exploration to deep sea fish and synthetic biology. NASA scientist Lynn Rothschild is a pioneer in the field of astrobiology, interested in probing the limits of life on earth, to better understand where we might find life signs elsewhere in the universe. Oliver Crimmen is the Fish Curator at the Natural History Museum in London. He's an expert on how some sea creatures can survive both freezing and hot water - and several miles beneath the surface of our oceans. And explorer Rosie Stancer takes her own body to the edge - with solo trips to both the South Pole and the Arctic North, and a new expedition planned across China's largest desert. (Image credit: Science Photo Library).