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As anti-science leaves research reeling, does evidence-based policy in a scientific society have much of a future? Michael Mann, Naomi Oreskes, Angie Rasmussen and Deb Houry discuss some of the sources and motivations that perhaps belie the current state of scientific affairs. Presenter: Roland Pease Producer: Alex Mansfield Production Coordinator: Jana Bennett-Holesworth (Image: The End street sign. Credit: Sanfel via Getty Images).